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Boceprevir药物的发现与进展：第一代丙型肝炎病毒NS3/4A丝氨酸蛋白酶抑制剂
The Discovery and Development of Boceprevir: A Novel, First-Generation Inhibitor of the Hepatitis C Virus NS3/4A Serine Protease
JCTH
PubMed (1 Sep 2013)
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抗癌药物的新机制的识别
A Melanocyte Lineage Program Confers Resistance to MAP Kinase Pathway Inhibition
Nature PubMed (5 Dec 2013)
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HDAC6能调节干细胞Tip60-P400的功能
Hdac6 Regulates Tip60-p400 Function in Stem Cells
Elife PubMed (4 Dec 2013)
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人甲型流感H7N9病毒特异性识别禽类样受体，因此尚未具备在人群中快速传播的能力
Preferential Recognition of Avian-Like Receptors in Human Influenza A H7N9 Viruses
Science PubMed (6 Dec 2013)
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DNA联合腺病毒为载体的HIV病毒疫苗临床试验
Efficacy Trial of a DNA/rAd5 HIV-1 Preventive Vaccine
Science PubMed (28 Nov 2013)
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新数码DNA技术通过定量肿瘤浸润淋巴细胞预测卵巢癌患者的存活率
Digital Genomic Quantification of Tumor-Infiltrating Lymphocytes
Sci Transl Med PubMed (4 Dec 2013)
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坎格雷洛在经皮冠状动脉介入治疗中对围手术期结果的影响
Effect of Cangrelor on periprocedural outcomes in percutaneous coronary interventions: a pooled analysis of patient-level data
Lancet PubMed (14 Dec 2013)
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从吸血蝙蝠的唾液腺中发现的新型抗凝血因子Desmolaris能抑制体内炎症反应和血栓形成
Desmolaris, A Novel Factor XIa Anticoagulant from the Salivary Gland of the Vampire Bat (Desmodus Rotundus) Inhibits Inflammation and Thrombosis In Vivo
Blood PubMed (12 Dec 2013)
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色氨酸生物合成可保护分枝杆菌免受T细胞介导的杀伤作用
Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing
Cell PubMed (5 Dec 2013)
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腺病毒独特的分泌型E3蛋白可结合白细胞共同抗原CD45以及调节白细胞功能
A Unique Secreted Adenovirus E3 Protein Binds to the Leukocyte Common Antigen CD45 and Modulates Leukocyte Functions
Proc Natl Acad Sci U S A PubMed (5 Dec 2013)
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胆汁酸增加microRNA221和222的水平从而导致CDX2的降解
Bile Acids Increase Levels of MicroRNAs 221 and 222, Leading to Degradation of CDX2 During Esophageal Carcinogenesis
Gastroenterology PubMed ( Dec 2013)
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体外受精所生的小鼠有血管功能障碍和寿命缩短等缺陷
Mice Generated by In Vitro Fertilization Exhibit Vascular Dysfunction and Shortened Life Span
J Clin Invest PubMed (2 Dec 2013)
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严重肥胖症患者减肥手术后3年内体重以及相关健康指标变化
Weight Change and Health Outcomes at 3 Years After Bariatric Surgery Among Individuals With Severe Obesity
JAMA PubMed (2 Dec 2013)
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依维莫司与索拉非尼联合使用治疗晚期肝癌的I期临床研究标变化
Phase I Study Investigating Everolimus Combined with Sorafenib in Patients with Advanced Hepatocellular Carcinoma
J Hepatol PubMed ( Dec 2013)
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心脏衰竭与高密度脂蛋白的抗炎及抗氧化功能受损有关
Heart Failure is Associated With Impaired Anti-Inflammatory and Antioxidant Properties of High-Density Lipoproteins
Am J Cardiol PubMed ( 1 Dec 2013)
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髋部骨折手术后，握力可用于预测持续行走恢复情况
Handgrip Strength Predicts Persistent Walking Recovery After Hip Fracture Surgery
Am J Med PubMed (Dec 2013)
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急性肾损伤及死亡在心胸手术中与肾素血管紧张素系统阻断相关：一项观察性研究的荟萃分析
Acute Kidney Injury and Death Associated With Renin Angiotensin System Blockade in Cardiothoracic
Am J Kidney Dis PubMed (Dec 2013)
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双阳性胸腺细胞能特异性选择粘膜相关不变的T细胞
Double Positive Thymocytes Select Mucosal-Associated Invariant T Cells
J Immunol PubMed (15 Dec 2013)
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CD36特异性抗体能阻断HIV-1从最初受感染的巨噬细胞中释放，进而阻断其延散感染T细胞
CD36-specific Antibodies Block Release of HIV-1 from Infected Primary Macrophages and its Transmission to T Cells
J Exp Med PubMed (18 Nov 2013)
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