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腺病毒载体介导的FIX基因治疗对B型血友病患者产生良好疗效
Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B
New Engl J Med
PubMed (22 Dec 2011)
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大鼠表现出和人类类似的移情作用驱使的帮助同类行为——移情作用的生物学基础
Empathy and Pro-Social Behavior in Rats
Science
PubMed (9 Dec 2011)
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芬特明/托吡酯控释剂能持续降低肥胖和超重人群的体重并促进代谢：随机安慰剂对照3期临床试验
Two-year Sustained Weight Loss and Metabolic Benefits with Controlled-release Phentermine/Topiramate in Obese and Overweight Adults (SEQUEL): a Randomized, Placebo-controlled, Phase 3 Extension Study
Am J Clin Nutr
PubMed (7 Dec 2011)
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- 新佐剂帕妥珠单抗和曲妥珠单抗在患有局部炎症或早期HER2阳性乳腺癌患者中的疗效和安全性：随机多中心开放式2期临床试验
Efficacy and Safety of Neoadjuvant Pertuzumab and Trastuzumab in Women with Locally Advanced, Inflammatory, or Early HER2-positive Breast Cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial
Lancet Oncol
PubMed (6 Dec 2011)
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血清中25(OH)D浓度50 nmol/L即足以抑制甲状旁腺激素分泌
The Relationship Between Serum 25(OH)D and Parathyroid Hormone Levels
Am J Med
PubMed (Dec 2011)
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主动免疫疗法可对癌症患者产生持续疗效：综述
Cancer Immunotherapy Comes of Age
Nature
PubMed (21 Dec 2011)
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- 基于干扰素的治疗能阻止并逆转HIV/HCV双重感染患者肝纤维化的进程
Influence of Interferon-based Therapy on Liver Fibrosis Progression in HIV/HCV Coinfected Patients: A Retrospective Repeated Liver Biopsy Analysis
J Hepatol
PubMed (Jan 2012)
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肾小球滤过压高于60 mL/min/1.73 m(2)的成年人中脉压、动脉弹性及内皮功能与肾功能衰退的相关性:动脉粥样硬化的多种族研究
Association of Pulse Pressure, Arterial Elasticity, and Endothelial Function with Kidney Function Decline Among Adults With Estimated GFR >60 mL/min/1.73 m2: The Multi-Ethnic Study of Atherosclerosis (MESA)
Am J Kidney Dis
PubMed (Jan 2012)
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蛲虫病并不能降低患哮喘、I型糖尿病等慢性炎性疾病风险：一项大规模人群队列研究
Helminth Infection Does Not Reduce Risk for Chronic Inflammatory Disease in a Population-Based Cohort Study
Gastroenterology
PubMed (Jan 2012)
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成年人口腔上皮干细胞的鉴定，体外扩增及其在角膜重建中的移植
Adult Human Buccal Epithelial Stem Cells: Identification, Ex-vivo Expansion, and Transplantation for Corneal Surface Reconstruction
Eye
PubMed (25 Dec 2011)
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肥胖与人类及啮齿动物大脑中的神经损伤相关
Obesity is Associated with Hypothalamic Injury in Rodents and Humans
J Clin Invest.
PubMed (27 Dec 2011)
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共生细菌通过诱导活性氧依赖性Toll激活途径控制埃及伊蚊中的登革热病毒
Wolbachia Induces Reactive Oxygen Species (ROS)-dependent Activation of the Toll Pathway to Control Dengue Virus in the Mosquito Aedes Aegypti
Proc Natl Acad Sci USA
PubMed (28 Nov 2011)
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鼠胚胎干细胞全基因组RNAi筛查揭示Mp1在细胞分化过程中起关键作用
A Genome-wide RNAi Screen in Mouse Embryonic Stem Cells Identifies Mp1 as a Key Mediator of Differentiation
J Exp Med
PubMed (19 Dec 2011)
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Th17细胞介导的粘膜免疫有可能开发出广谱抗菌疫苗
Th17 Cells Mediate Clade-Specific, Serotype-Independent Mucosal Immunity
Immunity
PubMed (23 Dec 2011)
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丙肝三联疗法在法国获得批准后的使用人数及相关费用：一项基于模型的分析研究
Impact of Hepatitis C Triple Therapy Availability upon the Number of Patients to be Treated and Associated Costs in France: a Model-based Analysis
Gut
PubMed (Feb 2012)
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能同时检测六种引起腹泻的细菌病原体的PCR-Luminex！
Simultaneous Detection of Six Diarrhea-Causing Bacterial Pathogens with an In-House PCR-Luminex Assay
J Clin Microbiol
PubMed (Jan 2012)
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富电子胶团通过使光敏剂从二类转变成一类光活化而提高光动力学疗法对肿瘤的疗效
Photoactivation Switch from Type II to Type I Reactions by Electron-rich Micelles for Improved Photodynamic Therapy of Cancer Cells under Hypoxia
J Control Release
PubMed (20 Dec 2011)
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指导性锻炼较支架植入对下周动脉疾病患者跛行疗效更好
Supervised Exercise Versus Primary Stenting for Claudication Resulting From Aortoiliac Peripheral Artery Disease: Six-Month Outcomes From the Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) Study
Circulation
PubMed (16 Nov 2011)
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早期干预能减少早产儿行为方面的问题：一项随机对照临床试验
Early Intervention Improves Behavioral Outcomes for Preterm Infants: Randomized Controlled Trial
Pediatrics
PubMed (Jan 2012)
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